אונקולוגיה והמטולוגיה
המרכז למחקר רפואי פלסנשטיין

חקר גידולי ראש צוואר ובסיס הגולגולת

המרכז למחקר רפואי פלסנשטיין

ראשי המחקר שלנו פרסומים נבחרים הצוות לכל המעבדות

חקר גידולי ראש צוואר ובסיס הגולגולת

פרסומים נבחרים

2018

  • Quantitative self-assembly prediction yields targeted nanomedicines.
    Shamay Y, Shah J, Işık M, Mizrachi A, Leibold J, Tschaharganeh DF, Roxbury D, Budhathoki-Uprety J, Nawaly K, Sugarman JL, Baut E, Neiman MR, Dacek M, Ganesh KS, Johnson DC, Sridharan R, Chu KL, Rajasekhar VK, Lowe SW, Chodera JD, Heller DA.
    Nat Mater. 2018 Apr;17(4):361-368. doi: 10.1038/s41563-017-0007-z. Epub 2018 Feb 5.
    למחקר

2019

  • Tumor Tissue Explant Culture of Patient-Derived Xenograft as Potential Prioritization Tool for Targeted Therapy.
    Ghosh S, Prasad M, Kundu K, Cohen L, Yegodayev KM, Zorea J, Joshua BZ, Lasry B, Dimitstein O, Bahat-Dinur A, Mizrachi A, Lazar V, Elkabets M, Porgador A.
    Front Oncol. 2019 Jan 22; 9:17. doi: 10.3389/fonc.2019.00017. eCollection 2019.
    למחקר
  • Sildenafil Protects Endothelial Cells from Radiation-Induced Oxidative Stress.
    Wortel RC, Mizrachi A, Li H, Markovsky E, Enyedi B, Jacobi J, Brodsky O, Cao J, Lippert AR, Incrocci L, Mulhall JP, Haimovitz-Friedman A.J
    Sex Med. 2019 Nov;16(11):1721-1733. doi: 10.1016/j.jsxm.2019.08.015. Epub 2019 Oct 1.
    למחקר

2020

  • Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma.
    Mizrachi A, Shamay Y, Shah J, Brook S, Soong J, Rajasekhar VK, Humm JL, Healey JH, Powell SN, Baselga J, Heller DA, Haimovitz-Friedman A, Scaltriti M.
    למחקר
  • Manipulating Oxidative Stress Following Ionizing Radiation. .
    Haimovitz-Friedman A, Mizrachi A, Jaimes EA
    Cell Signaling. 2020;1(1):8-13. doi: 10.33696/signaling.1.003.
    למחקר
  • CDK 4/6 Inhibition Overcomes Acquired and Inherent Resistance to PI3Kα Inhibition in Pre-Clinical Models of Head and Neck Squamous Cell Carcinoma .
    Eric Remer, Mai Badarni, Elad Hikri, Avraham Dayan, Lirit Levi, Aron Popovtzer, Muhammed Iraqi, Angel Porgador, Ben-Zion Joshua, Gideon Bachar, Moshe Elkabets, Maurizio Scaltriti, Aviram Mizrachi.
    Clinical Medicine. 2020 Oct 7;9(10):3214
    למחקר

2021

  • Chemotherapy-induced acute vascular injury involves intracellular generation of ROS via activation of the acid sphingomyelinase pathway.
    Aviram Mizrachi, Irit Ben-Aharon, Hongyan Li, Hadas Bar-Joseph, Chloe Bodden, Elad Hikri, Aron Popovtzer, Ruth Shalgi, Adriana Haimovitz-Friedman.
    Cell Signaling 2021 Jun;82:109969
    למחקר

2022

  • The protective effect of aspirin-induced temporary threshold shift in an animal model of cisplatin-related ototoxicity.
    Tzelnick S, Mizrachi A, Barkan N, Shivatzki S, Yosefof E, Hikri E, Attias J, Hilly O. J
    Cancer Res Clin Oncol. 2022 Jul 1.
    למחקר

2023

  • Effect of Opioid Receptor Activation and Blockage on the Progression and Response to Treatment of Head and Neck Squamous Cell Carcinoma .
    Levi L, Hikri E, Popovtzer A, Dayan A, Levi A, Bachar G, Mizrachi A, Shoffel-Havakuk H. J Clin
    Med. 2023 Feb 6;12(4):1277. doi: 10.3390/jcm12041277.
    למחקר

2025

  • Targeted apoptotic immune modulator for the treatment of metastatic EGFR-positive solid tumors.
    Derrick Broka, Shoshana Klein, Alexei Shir, Babette Schade, Meera Saxena, Athanasia Dasargyri, Anita Jarzebinska, Caroline De Feyter, Davor Bajic, David Colecchia, Lucia D'Amico, Eric Kitas, Elad Hikri, Michal Jerzy Skowicki, Michal Jerzy Okoniewski, Laura Baldino, Besnik Qeriqi, Elisa de Stanchina, Joerg Schreiber, Melanie Buchi, Cornelia G Palivan, Yaakov Benenson, Alfred Zippelius, Doriano Fabbro, Maurizio Scaltriti, Aviram Mizrachi, Alexander Levitzki, Esteban Pombo-Villar, Maya Zigler. Proc Natl Acad Sci
    USA. 2025 Jun 3;122(22):e2500489122.
    למחקר
  • N-Acetylcysteine Amide Is a Potential Novel Radioprotector of Salivary Gland Function.
    Amit Ritter, Elad Hikri, Hongyan Li, Ela Markovsky, Gideon Bachar, Noga Kurman, Aron Popovtzer, Adriana Haimovitz-Friedman, Aviram Mizrachi. .
    Cancers (Basel). 2025 Sep 4;17(17):2902
    למחקר

ראש/ת המעבדה

פרופ' גדעון בכר .M.D.

מנהל/ת המעבדה

ד"ר דן יניב M.D

יצירת קשר

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